Inclusion Criteria:

• Be 18 years or older

• Be willing to sign an informed consent approved by Ethic Committee (when applicable) or not being opposed to the use of their clinical data in the study

  o For prospective inclusion:

• Be considered for treatment with one of the TEKNIMED Spine Range cement comprised in this study

  o For retrospective inclusion:

• Have undergone a surgery with a TEKNIMED Spine Range cement between the 1st of January 2016 and the date of the site initiation visit.

• Be informed of the study and not being opposed to the use of their clinical data in the study or be willing to sign an informed consent during the first follow-up visit following the site initiation (when applicable).

Exclusion Criteria:

Patients presenting one of the following conditions will not be included (contraindications per IFU):

• Procedures other than those stated in the INDICATIONS section
• Coagulation disorders, or severe cardiopulmonary disease
• Unstable vertebral fractures
• Compromise of the vertebral body or of the pedicle walls
• Hypersensitivity or allergy to one of the constituents of the product
• Patient clearly improving on more conservative treatment
• Prophylactic use in spinal metastatic or osteoporotic patients with no evidence of acute fracture
• Paediatric patients and pregnant or breast-feeding women.