Evaluation of 3D DL oZTEo MRI Pulse Sequence to Detect Bone Changes in Patients with Inflammatory Arthritis

What this Trial Is About

Researchers are evaluating a new MRI pulse sequence called 3D DL oZTEo to improve the detection of bone erosions in the hands of patients with inflammatory arthritis. Detecting these bone changes is important for managing rheumatic conditions like rheumatoid arthritis and can also help with diagnosis. Currently, bone erosions are mostly assessed using standard X-rays and conventional MRI scans. The study adds the FDA-approved oZTEo MRI pulse sequence to the usual MRI exam of the hand. The images from this sequence will be anonymized and sent to GE Healthcare, where a deep learning algorithm called 3D DL will be applied to analyze the scans. This approach aims to validate whether the new technique can better detect bone erosions compared to current methods. Participants are adult patients scheduled for a hand MRI as part of their regular clinical care and who have had hand X-rays confirming bone erosions within the past 3 to 6 months. The presence or absence of bone erosions will be measured using MRI scans with and without the new 3D DL oZTEo sequence, with results evaluated on the same day. The study helps assess if this technology can enhance detection of osseous changes in inflammatory arthritis.

3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis