Status:
RECRUITING
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Lead Sponsor:
University of Washington
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Critical Illness
Delirium
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge. Older ICU survivors ...
Detailed Description
Using a 2 x 2 factorial design, 100 English- or Spanish-speaking older ICU survivors will be enrolled after discharge out of ICU and randomized to one of 4 combinations of two interventions: SLEEP and...
Eligibility Criteria
Inclusion Criteria:
- Age greater than or equal to 60 years old
- Current hospitalization at University of Washington Medical Center or Harborview Medical Center
- Intensive care unit (ICU) length of stay greater than 24 hours
- Recovery from critical care status to acute care status, and/or discharge out of ICU
- Fluent in English or Spanish
- Functional independence on activities of daily living prior to hospitalization (Katz Index = 6)
Exclusion Criteria:
- Documented history or suspicion of Alzheimer's disease or dementia, or current prescription of anti-dementia medication
- Documented history of bipolar disorder or schizophrenia
- Documented acute stroke or traumatic brain injury
- Severe vision impairment
- Severe hearing impairment
- Severe paralysis or dominant arm paresis
- Transfer from skilled nursing care facility or inpatient rehabilitation facility
Key Trial Info
Start Date :
December 26 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06411561
Start Date
December 26 2024
End Date
May 31 2027
Last Update
July 20 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Washington
Seattle, Washington, United States, 98195