Status:

RECRUITING

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

Lead Sponsor:

National Cancer Centre, Singapore

Conditions:

Advanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung Cancer

Eligibility:

All Genders

21-99 years

Brief Summary

There are limited in depth studies on the epidemiology and clinical management of EGFR exon 20 insertion mutated NSCLC in Asia. In addition, there is preliminary data suggesting the exact location of ...

Detailed Description

This study will be a multi-center observational study and will enroll patients with advanced EGFR exon 20 insertion mutated NSCLC. The study will include patients recruited from countries across Asia...

Eligibility Criteria

Inclusion Criteria:

  1. Histologically confirmed advanced NSCLC
  2. Positive testing result from any locally approved test (including but not limited to RT-PCR, Cobas and NGS) for EGFR exon 20 insertion mutation
  3. Diagnosis date from 1 Jan 2013 to 31 Dec 2024 (to allow for minimum 12 months of follow-up clinical and treatment outcome data)
  4. Male or female adults, age as defined by local regulations

Exclusion Criteria:

1. Patients without an EGFR exon 20 insertion mutation

Key Trial Info

Start Date :

March 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT06418412

Start Date

March 15 2024

End Date

December 31 2026

Last Update

June 12 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

National Cancer Centre, Singapore

Singapore, Singapore, 168583

2

Seoul National University Hospital

Seoul, South Korea

3

National Taiwan University Hospital

Taipei, Taiwan