Status:

RECRUITING

Bupivacaine and Epinephrine Injection Study

Lead Sponsor:

Amin Javer

Conditions:

Sinus Disease

Anesthesia

Eligibility:

All Genders

19+ years

Phase:

PHASE2

PHASE3

Brief Summary

Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical m...

Eligibility Criteria

Inclusion Criteria:

  • Age 19 years or older
  • Scheduled for primary ESS (including septoplasty)

Exclusion Criteria:

  • Cystic fibrosis
  • Systemic vasculitis or any bleeding disorders
  • Known or suspected hypersensitivity to bupivacaine or epinephrine
  • Previous sinus surgery
  • Inhaled drug use (i.e., cocaine) in the preceding 6 months
  • Nasal tumors
  • Patients on antiarrhythmics.
  • Patients with history of severe liver illness.
  • Patients identified as high-risk for complications during preoperative assessment with the anesthesiologist (e.g. untreated hypertension, ischemic heart disease, cerebral vascular insufficiency, heart block, peripheral vascular disorder, uncontrolled hyperthyroidism and diabetes)

Key Trial Info

Start Date :

November 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06456255

Start Date

November 15 2024

End Date

July 1 2025

Last Update

May 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

St.Paul's Hospital Sinus Center

Vancouver, British Columbia, Canada, V6Z 1Y6