Status:

RECRUITING

The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery

Lead Sponsor:

Umraniye Education and Research Hospital

Conditions:

Anesthesia

Gynecologic Cancer

Eligibility:

FEMALE

18-70 years

Phase:

NA

Brief Summary

The aim of the study was to determine whether the use of different mechanical ventilation modes in patients with Trendelenburg position and CO2 insufflation affects respiration and cerebral oxygenatio...

Detailed Description

In laparoscopic interventions, the Trendelenburg position should be applied and artificial pneumoperitoneum should be created by CO2 insufflation. Trendelenburg position is widely used in laparoscopic...

Eligibility Criteria

Inclusion

  • 18-70 age
  • ASA 1-3

Exclusion

  • Under 18 years of age, over 70 years of age,
  • ASA IV,
  • history of severe chronic obstructive pulmonary disease (COPD, GOLD III or IV)
  • ,-history of severe or uncontrolled bronchial asthma, presence of restrictive lung disease,
  • history of any thoracic surgery operation, need for thoracic drainage before surgery
  • patients receiving preoperative renal replacement therapy,
  • congestive heart failure (NYHA grade III or IV),
  • extremely obese (body Mass Index, BMI \> 35 Kg/m2)
  • patients without patient consent

Key Trial Info

Start Date :

May 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06482983

Start Date

May 1 2023

End Date

July 31 2026

Last Update

November 19 2025

Active Locations (1)

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Umraniye research and education hospital

Istanbul, Umraniye, Turkey (Türkiye), 34764