Status:

RECRUITING

Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients

Lead Sponsor:

Istituto Ortopedico Rizzoli

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

The study consists of 3 phases (enrollment, infiltrative procedure, and controls): * Identification by specialized orthopedic medical staff belonging to the SC Orthopedic and Trauma Clinic II of the ...

Eligibility Criteria

Inclusion

  • Patients, both sexes, with symptomatic knee osteoarthritis with:
  • Age: 18-40 years;
  • Unilateral involvement;
  • Signs and symptoms of knee osteoarthritis;
  • Radiographic or MRI signs of degenerative pathology of knee cartilage (Kellgren-Lawrence grade 1-3);
  • Ability and consent of patients to actively participate in clinical follow-up;
  • Signature of informed consent;
  • Pain ≥ 4 on VAS s

Exclusion

  • Patients unable to express consent;
  • Patients undergoing intra-articular infiltration of other substance in the previous 6 months;
  • Patients undergoing knee surgery in the previous 12 months;
  • Patients with malignant neoplasms;
  • Patients with rheumatic diseases;
  • Patients with uncontrolled metabolic diseases;
  • Patients with hematological diseases (coagulopathies);
  • Patients abusing alcoholic beverages, drugs or medications;
  • Knee trauma treated in the previous 6 months.
  • Other conditions that may interfere with the evaluation of OA treatment.

Key Trial Info

Start Date :

October 10 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06483269

Start Date

October 10 2023

End Date

September 1 2026

Last Update

July 4 2025

Active Locations (1)

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IRCCS - Istituto ortopedico Rizzoli

Bologna, Italy, 40136