Deciphering How Food Intake Affects Sleepiness and Nighttime Sleep Quality in People With Type 1 Narcolepsy and Idiopathic Hypersomnia

What this Trial Is About

Researchers are studying how food intake, sleepiness, and nighttime sleep quality interact in people with Type 1 Narcolepsy (NT1), Idiopathic Hypersomnia (IH), and healthy individuals. The study aims to better understand why obesity occurs frequently in NT1 patients and rarely in IH patients, focusing on how diet, body composition, and sleep patterns affect sleepiness and weight. The research explores whether eating high glycemic index foods increases sleepiness and how this might contribute to obesity in NT1 compared to IH and healthy controls. Participants will be monitored over several days using different devices and methods. Eating behaviors will be tracked through photos of meals taken with smartphones and a glucose sensor worn on the arm to monitor sugar intake. Sleep and wake patterns will be recorded using a sleep diary and an actigraphy device. Nighttime sleep quality and brain activity related to sleepiness will be measured with a portable sleep device called SOMFIT. Sleepiness will be assessed using a sleepiness scale at meal times and EEG markers recorded by the SOMFIT device. During the study, participants will provide data on their body mass index, body composition, and complete questionnaires about sleep quality, mood, and eating habits. The study will measure how glycemic load impacts sleepiness after lunch over three days. Researchers will analyze all these factors to understand the links between eating habits, sleepiness, and obesity. The overall study duration includes 4 to 5 days of at-home monitoring and assessments to gather comprehensive information.

Deciphering the Interactions Between Food Intake, Sleepiness, and Nighttime Sleep Quality in Patients With Type 1 Narcolepsy and Idiopathic Hypersomnia