Status:

COMPLETED

Predictive Urodynamic Parameters for The Treatment Efficacy of Onabotulinum A Toxin in Neurogenic Lower Urinary Tract Dysfunction

Lead Sponsor:

University of Gaziantep

Conditions:

Neurogenic Bladder Disorder

Eligibility:

All Genders

18+ years

Brief Summary

Purpose: To evaluate urodynamic parameters predicting the treatment efficacy of onabotulinumtoxin A (onaBoNT-A) in patients with neurogenic lower urinary tract dysfunction (NLUTD). Methods: Patients ...

Eligibility Criteria

Inclusion

  • Patients with Neurogenic Lower Urinary Tract Disorder
  • Aged \>18 years
  • Patients who did not respond adequatel to antimuscarinics or could not tolerate their side effects
  • Antimuscarinic treatment failure with at least two different antimuscarinic agents for a minimum of 3 months.

Exclusion

  • Patients with Lower Urinary Tract Disorder due to functional or non-neurogenic etiologies
  • Patients who received onaBoNT-A doses either other than 200 IU or its multiple doses
  • In the 12-month period designated for patient follow-up, patients who did not attend their check-ups

Key Trial Info

Start Date :

September 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2024

Estimated Enrollment :

74 Patients enrolled

Trial Details

Trial ID

NCT06485453

Start Date

September 1 2013

End Date

June 1 2024

Last Update

July 3 2024

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