Status:
RECRUITING
Action Regulation Behavioral
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
University of California, Riverside
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Parkinson's disease (PD) is a neurodegenerative disorder involving a part of the brain that is responsible for motor control, which not only results in changes or disruptions in movement, but also cog...
Eligibility Criteria
Inclusion
- For Parkinson's Disease Patients:
- Diagnosis of Parkinson's Disease by a movement disorder neurologist
- Levodopa responsive with clearly defined "on" periods, with at least 30% improvement in UPDRS III scores on vs off
- Willingness and ability to complete the behavioral experiments for up 3.5 hours
- No vision or hearing problems that impair ability to participate with the proposed tasks as assessed by the study investigators
Exclusion
- Patients with history of secondary Parkinsonism, stroke, or progressive central nervous system disease other than Parkinson's Disease
- Patients with a disease or condition that prevents understanding or communication of informed consent, study demands, and testing protocol including cognitive decline, diagnosed forms of dementia, significant memory impairment (MoCA\<23), or hearing loss that prevents adequate communication with researcher
- For Healthy subjects:
- Inclusion Criteria:
- No history any diagnosed neurological disease(s), including movement disorders or cognitive decline
- No vision or hearing problems that impair ability to participate with the proposed tasks as assessed by the study investigators
Key Trial Info
Start Date :
April 24 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06489483
Start Date
April 24 2024
End Date
November 1 2027
Last Update
December 12 2025
Active Locations (1)
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1
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75390