Status:

NOT_YET_RECRUITING

HAPH Registry: Time Course and Prognostic Significance of Pulmonary Artery Pressure in Highlanders.

Lead Sponsor:

University of Zurich

Collaborating Sponsors:

National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov

Conditions:

High Altitude Pulmonary Hypertension

Sleep Apnea

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the current study is to evaluate the clinical and physiologic course of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study. To...

Eligibility Criteria

Inclusion

  • Permanently living \>2500 m
  • Written informed consent

Exclusion

  • Highlanders who cannot follow the study investigations,
  • Patients with moderate to severe concomitant lung disease (FEV1\<70% or forced vital capacity \<70%), severe parenchymal lung disease, heavy smoking \>20 cigarettes/day or \>20 pack-years.
  • Coexistent unstable systemic hypertension or coronary artery disease that required adjustment of medication within the last 2 months
  • Regular use of medication that affects control of breathing (benzodiazepines, opioids, acetazolamide)

Key Trial Info

Start Date :

July 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06489730

Start Date

July 1 2024

End Date

December 31 2024

Last Update

July 8 2024

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