Status:
RECRUITING
Coding of Speech Signals in the Human Auditory Nerve
Lead Sponsor:
CHU de Reims
Conditions:
Hearing Loss
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situa...
Detailed Description
The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situa...
Eligibility Criteria
Inclusion
- inclusion criteria :
- Will be included as hearing impaired patients:
- male or female
- over 18 years of age
- who are to undergo surgery on the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor)
- with a mild to severe sensorineural hearing loss defined by an average hearing loss (average of thresholds obtained at 500, 1000, 2000 and 4000 Hz) greater than 20 dB and less than 90 dB in pure tone bone conduction audiometry on the side of the operated ear.
- affiliated to a social security system.
- have read the information note describing the study and have agreed in writing to participate by signing the informed consent form.
- Will be included as normal hearing patients:
- male or female
- over 18 years of age
- who are to undergo surgery in the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor)
- free of neuro-sensory deafness, defined by average hearing thresholds less than or equal to 20 dB in tonal bone conduction audiometry on the side of the operated ear
- affiliated with a social security system.
- having read the information note describing the study and having agreed in writing to participate by signing the informed consent form.
- exclusion criteria :
- Patients for whom the auditory nerve is not accessible during surgery,
- because of a complete tumor invasion of the cochlear nerve (stage III and IV neuroma, advanced meningioma)
- because of an anatomical feature not identified during the preoperative examination, making its exposure for recordings impossible (protrusion of the posterior face of the rock)
Exclusion
Key Trial Info
Start Date :
December 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 7 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06490237
Start Date
December 7 2021
End Date
June 7 2027
Last Update
July 8 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Damien JOLLY
Reims, France