Status:

RECRUITING

Analysis of the Pathophysiological and Functional State of the Knee Joint

Lead Sponsor:

Istituto Ortopedico Rizzoli

Conditions:

Osteoarthritis, Knee

Cartilage Degeneration

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Osteoarthritis is the most common degenerative condition affecting the knee joint globally, with an incidence of about 7% of the population. In Italy, it affects approximately 3.9 million people, with...

Eligibility Criteria

Inclusion

  • Knee pain and/or loss of functionality
  • Kellgren-Lawrence grade less than or equal to 2
  • Arthroscopic evidence of cartilage tissue lesions
  • Evidence of cartilage and/or meniscal tissue degeneration and/or subchondral bone marrow lesions

Exclusion

  • History/evidence of previous partial or total knee prosthesis interventions
  • Inability to provide informed consent
  • Conditions or physical disorders incompatible with the use of MRI and electrical stimulation (implanted active and passive biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)

Key Trial Info

Start Date :

July 9 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT06490770

Start Date

July 9 2025

End Date

April 1 2027

Last Update

July 17 2025

Active Locations (1)

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1

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy, 40136