Status:
RECRUITING
RACE-2L: Real-World Assessment of Clinical Practice and Outcomes in Non-squamous NSCLC After Failure of Platinum-based Chemotherapy in Brazil
Lead Sponsor:
AstraZeneca
Conditions:
Non-squamous Non-Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The study will be implemented as a retrospective, noninterventional medical record review of patients from routine practice settings who have been diagnosed with a/m non-squamous NSCLC with or without...
Detailed Description
The study will be implemented as a retrospective, noninterventional medical record review of patients from routine practice settings who have been diagnosed with advanced/metastaic non-squamous NSCLC ...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Confirmed diagnosis of patients with non-squamous NSCLC stage IIIB/IIIC not eligible for curative-intent therapies or stage IV/M1 (a/m NSCLC) with or without actionable genomic mutations (i.e., EGFR, ALK, ROS1, NTRK, BRAF, MET exon 14 skipping, RET, HER-2)
- Aged at least 18 years at first diagnosis of a/m NSCLC
- For the AGA subgroup, having received platinum-based chemotherapy, having received at least one target approved therapy.
- For the non\_AGA subgroup,should have received either sequential or concurrent use of ICI and PTC)
- Patient must have received at least line of therapy of an active agent after failing PTC.
- Exclusion Criteria
- Patients with evidence of other primary malignancies (apart from basal cell carcinoma and melanoma) within 1 year prior to the index date will be excluded from both the study cohorts.
- Patients who participated in an investigational clinical trial for the treatment of any cancer, including NSCLC, or any early access program from 2018 onward.
Exclusion
Key Trial Info
Start Date :
July 25 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT06491862
Start Date
July 25 2024
End Date
June 30 2026
Last Update
December 12 2025
Active Locations (11)
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1
Research Site
Belo Horizonte, Minas Gerais, Brazil, 30110-934
2
Research Site
Belo Horizonte, Minas Gerais, Brazil, 30380-420
3
Research Site
Natal, Rio Grande do Norte, Brazil, 59062-000
4
Research Site
Porto Alegre, Rio Grande do Sul, Brazil, 90560-032