Status:
RECRUITING
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
Lead Sponsor:
Zhongshan Ophthalmic Center, Sun Yat-sen University
Conditions:
Angle-closure Glaucoma
Minimally Invasive Glaucoma Surgery
Eligibility:
All Genders
30-85 years
Brief Summary
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma. Minimally invasive glauco...
Detailed Description
Pathological elevated intraocular pressure is one of the most important disease characteristics of glaucoma. Blockage of aqueous humor outflow within the eye is the primary cause of high intraocular p...
Eligibility Criteria
Inclusion
- Glaucoma patients eligible for standalone or combined angle intervention surgeries, such as LPI, LPIP, goniosynechialysis, trabeculotomy alone or combined with surgical iridectomy or phacoemulsification and intraocular lens implantation;
- Patients capable of undergoing preoperative examinations including CASIA2-OCT (anterior segment OCT), UBM, slit-lamp gonioscopy, IOL Master (or other optical biometry);
- Patients willing to participate in this study, signing informed consent, and agreeing to follow-up according to the study protocol.
Exclusion
- Patients with severe ocular conditions such as corneal infection, ulcer, trauma, ocular tumors, retinal vascular occlusion, and retinal detachment;
- Those with various types of eye diseases that affect ocular parameter acquisition or interfere with visual field examination;
- Long-term local or systemic use of glucocorticoids;
- Patients with severe systemic diseases;
- Pregnant or lactating women;
- Unable to complete 12-month postoperative follow-up.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06492538
Start Date
December 1 2023
End Date
December 30 2025
Last Update
December 12 2025
Active Locations (1)
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1
Zhongshan ophthalmic center
Guangzhou, Guangdong, China, 51006dddddd0