Status:

RECRUITING

Gene Therapy(FT-003) for Wet AMD

Lead Sponsor:

Frontera Therapeutics

Collaborating Sponsors:

Tianjin Medical University Eye Hospital

The First Affiliated Hospital of Soochow University

Conditions:

Neovascular Age-related Macular Degeneration

Eligibility:

All Genders

50-80 years

Phase:

PHASE1

PHASE2

Brief Summary

The goal of this clinical trial is to evaluate the safety, tolerability and efficacy of disposable vitreous injection of FT-003 in subjects with neovascular age-related Macular Degeneration (nAMD). Th...

Detailed Description

FT-003 is a gene therapy product developed for the treatment of neovascular age-related macular degeneration (nAMD). Neovascular AMD is the main cause of blindness among elderly individuals. The avail...

Eligibility Criteria

Inclusion

  • Subjects that are willing and able to follow study procedures;
  • Female or male patients 50-80 years old at the time of signing the ICF;
  • Clinically diagnosed with nAMD;
  • Presence of active CNV
  • The best corrected visual acuity (BCVA) of the studied eye is 24-73 letters;

Exclusion

  • •Presence of any other intraocular diseases other than nAMD in the studied eye that would affect the improvement of visual acuity and require treatment during the study for prevention or treatment of visual loss, as judged by the investigator.

Key Trial Info

Start Date :

August 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 15 2028

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT06492863

Start Date

August 15 2023

End Date

October 15 2028

Last Update

July 9 2024

Active Locations (1)

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Tianjin Medical University Eye Hospital

Tianjin, Tianjin,China, China, 300392