Status:
NOT_YET_RECRUITING
Effect of Opioid-free Anesthesia on Sleep Quality, Cognitive Function and Recovery Quality After General Anesthesia in Elderly Patients
Lead Sponsor:
Beijing Friendship Hospital
Conditions:
Opioid-Free Anesthesia
POCD
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Postoperative cognitive dysfunction (POCD)is a common well disorder of the central nervous system after surgery, mainly manifested by impaired memory, spirit, language ability or other aspects of brai...
Eligibility Criteria
Inclusion
- Elderly patients to undergo elective non-cardiac surgery
- ASA grade I or III;
- volunteered in this trial and signed informed consent;
- age 60 years;
- BMI 18-30kg / m2.
Exclusion
- Chronic pain;
- severe liver dysfunction (total bilirubin 2 mg dl-1);
- severe renal dysfunction (glomerular filtration rate 60ml min-1 1.73m-2);
- preoperative heart rate \<50 beats / min, sick sinus syndrome, severe heart block;
- dementia or significant neurological disease (such as stroke, epilepsy, intracranial tumor, Parkinson disease, etc);
- history of alcohol or drug abuse;
- preoperative or PSQI score 7 or sleep disturbance;
- Cannot cooperate with the scale survey
- Allergic to the trial drug
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2025
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT06493396
Start Date
August 1 2024
End Date
August 31 2025
Last Update
July 10 2024
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