Status:

RECRUITING

Positive Minds Strong Joints for Knee Osteoarthritis

Lead Sponsor:

Boston University Charles River Campus

Collaborating Sponsors:

Rheumatology Research Foundation

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).

Detailed Description

In this feasibility study, at least 20 and up to 40 Black Adults will be enrolled to receive PMSJ intervention. Participants who will take part in this research study will be in it for about 26 weeks....

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Age≥50
  • BMI ≤ 40 kg/m2
  • Self-identify as Black (including African American)
  • Knee pain ≥4/10 on a 11 numeric scale over the past week
  • Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7)
  • Can speak and understand English at a sufficient level to understand the study procedures and informed consent
  • Available for study duration
  • Able to attend remote sessions
  • EXCLUSION CRITERIA
  • Knee, hip or ankle replacement
  • Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months
  • Knee surgery within past 6 months
  • Currently receiving or received within 3-months any PT for knee OA
  • Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments)
  • Planning to initiate physical therapy for joint or low back pain in the next 3months
  • Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month.
  • Systemic inflammatory arthritis (e.g., rheumatoid arthritis)
  • Neurologic conditions (e.g., stroke, Parkinson's disease, etc.)
  • Contraindications to starting an exercise program.
  • Suspected substance abuse
  • Lack capacity to consent
  • Pregnancy (self-report)
  • Participation in another clinical trial for any joint or muscle pain
  • Planning for a major surgery in the next 6 months
  • Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, psychosis, schizophrenia)
  • Receiving chemotherapy or radiation therapy for cancer (except non-melanoma skin cancer)

Exclusion

    Key Trial Info

    Start Date :

    February 17 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 30 2026

    Estimated Enrollment :

    40 Patients enrolled

    Trial Details

    Trial ID

    NCT06493903

    Start Date

    February 17 2025

    End Date

    December 30 2026

    Last Update

    May 16 2025

    Active Locations (1)

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    Boston University

    Boston, Massachusetts, United States, 02215