Status:
RECRUITING
Efficacy and Safety of tACS vs tDCS in Schizophrenia
Lead Sponsor:
All India Institute of Medical Sciences, Bhubaneswar
Collaborating Sponsors:
Indian Council of Medical Research
Conditions:
Schizophrenia
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
This clinical trial aims to compare the efficacy and safety of transcranial Alternating current stimulation (tACS) vs. transcranial Direct current stimulation (tDCS) vs. sham stimulation in chronic sc...
Detailed Description
The proposed double-blind RCT will be conducted over 3 years involving 2 centres among patients with chronic schizophrenia (moderate-severe symptoms) of either gender, aged between 18 and 60. Those wi...
Eligibility Criteria
Inclusion
- Diagnosis of Schizophrenia as per ICD-10 DCR for more than 2 years
- Moderate-severe symptoms (PANSS score \> 75 and/or CGI-SCH score\>4) \[24\]
- On stable dosing of antipsychotic medications (no changes in medication or doses for 1 month prior to enrolment)
- Both sexes; Age range: 18-60 years
- Right-handed
- Written informed consent by the patient
Exclusion
- Features suggestive of psychiatric emergency (for example: suicidal risk, catatonia, prolonged nutritional deprivation) or others (for example: aggression or excitement)
- Any contraindication to tDCS procedure: Metal in the head, Implanted brain medical devices, Local lesion or injury in the scalp / head
- Co-morbid neurological disease
- Left Handed
Key Trial Info
Start Date :
April 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06494124
Start Date
April 3 2024
End Date
June 1 2026
Last Update
July 10 2024
Active Locations (1)
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1
All India Institute of Medical Scinces - Bhubaneswar
Bhubaneswar, Odisha, India, 751019