Status:

RECRUITING

The Influence of Using Vascularized Vaginal Flap on the Efficacy of Mesh-augmented Sacrospinous Hysteropexy

Lead Sponsor:

Saint Petersburg State University, Russia

Conditions:

Pelvic Organ Prolapse

Eligibility:

FEMALE

45-80 years

Phase:

NA

Brief Summary

This is a prospective randomized controlled trial designed to compare the effectiveness and safety of two methods of pelvic floor reconstruction in patients with pelvic organ prolapse (POP): sacrospin...

Detailed Description

BACKGROUND POP is an epidemiologically widespread condition, occurring in 40-60% of women who have given birth. With all the variety of anatomical defects of the pelvic floor, the most common variant ...

Eligibility Criteria

Inclusion

  • The subject is a woman with anterior and apical compartment pelvic organ prolapse
  • The age of a subject is 45-80 years
  • Leading point of prolapse is at the level of the hymen or distal to the hymen (Ba, C\>=1 according to POP-Q classification)
  • The subject gave written consent to participate in the study
  • The subject is able to evaluate the risks of the treatment and make an independent decision on participation in the study
  • The subject is able to fill up validated questionnaires and come to the control visit after the surgery

Exclusion

  • The subject has an active urinary tract infection or skin infection in the region of surgery or acute infectious disease
  • The subject had prior hysterectomy
  • The subject has previously diagnosed or currently active cancer
  • The subject has chronic pelvic pain
  • The subject has cervical elongation
  • The subject has gynecological diseases (recurrent uterine bleeding, endometrial hyperplasia, the presence of atypical cells in cervical smears, adenomyosis, multiple uterine myoma)
  • The subject is planning pregnancy
  • The subject is unable to visit postoperative check-ups
  • Refusal from participation.

Key Trial Info

Start Date :

May 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06494982

Start Date

May 1 2024

End Date

October 1 2025

Last Update

July 10 2024

Active Locations (1)

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1

Saint-Petersburg State University Hospital

Saint Petersburg, Russia, 190103