Status:

ENROLLING_BY_INVITATION

Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors

Lead Sponsor:

Al-Azhar University

Conditions:

Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement

Eligibility:

All Genders

15-25 years

Phase:

NA

Brief Summary

The aim of this prospective clinical study will be to compare the efficacy of micro osteoperforations versus injectable platelet-rich fibrin during orthodontic leveling and alignment of mandibular inc...

Eligibility Criteria

Inclusion

  • An age range from 15 to 25 years.
  • Participants who had a full set of permanent dentitions excluding the third molar.
  • Participants who had moderate crowding in the mandibular arch according to Little's irregularity index that necessitates non-extraction treatment in the mandibular arch.
  • Normal vertical facial proportions.
  • Participants who had good oral hygiene and no periodontal disease.
  • No systemic diseases or regular medication that could interfere and/or affect orthodontic teeth movement.
  • No evidence of craniofacial anomalies, such as clef lip and palate or previous history of trauma, bruxism, or parafunction.
  • No tooth size, shape, or root abnormalities visible on patient's radiographic records.

Exclusion

  • Previous orthodontic treatment.
  • Any skeletal dysplasia or craniofacial malformation.
  • Retained primary or missing permanent teeth in the anterior area, and any kind of tooth/root shape anomaly or history of trauma affecting the incisors.
  • Systemic diseases or regular use of medications that could interfere with OTM.
  • Patients with root resorption, impacted canines, or dental anomalies.
  • Poor oral hygiene and uncontrolled periodontal diseases.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT06498609

Start Date

August 1 2024

End Date

December 1 2024

Last Update

July 12 2024

Active Locations (1)

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1

Alazhar University

Cairo, Egypt