Status:

NOT_YET_RECRUITING

Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery

Lead Sponsor:

Ciusss de L'Est de l'Île de Montréal

Collaborating Sponsors:

Institut de Cardiologie de Montréal

Conditions:

Gastric Retention

Eligibility:

All Genders

18+ years

Brief Summary

Glucagon-like peptide-1 agonists (GLP-1RA) are a family of medications used for diabetes and weight loss. One of their effect is to slow down stomach emptying. The goal of this study is to evaluate th...

Detailed Description

Background: Glucagon-like peptide-1 receptor agonists (GLP-1RA) are glucose-lowering drugs that act through three mechanisms: stimulation of insulin secretion, inhibition of glucagon secretion and dec...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiologists (ASA) class 1-4 patients
  • Age ≥ 18 years old
  • Fasted state (2 hours for clear liquids, 6 hours for solids)
  • Elective surgery
  • Last dose of once-weekly semaglutide or dulaglutide 7 days or more before surgery (for GLP-1RA group)

Exclusion

  • Last dose of GLP-1RA less than 7 days before surgery
  • Inability to lay on the right-side for ultrasound
  • Pregnancy
  • History of gastric surgery or large hiatal hernia

Key Trial Info

Start Date :

September 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2025

Estimated Enrollment :

94 Patients enrolled

Trial Details

Trial ID

NCT06500143

Start Date

September 1 2024

End Date

March 1 2025

Last Update

July 16 2024

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