Status:

COMPLETED

Determining the Dose Response Profile of the Headward Fluid Shift During Varying Gravity Levels

Lead Sponsor:

National Aeronautics and Space Administration (NASA)

Collaborating Sponsors:

NOVESPACE (Merignac, France)

European Space Agency

Conditions:

Healthy

Eligibility:

All Genders

25-55 years

Phase:

NA

Brief Summary

Parabolic flight provides a unique opportunity to evaluate the acute changes associated with varying levels of gravity and to describe how key venous parameters change at levels less than normal Earth...

Detailed Description

Subjects first will be studied for baseline data collection (BDC) on Earth in a 1 gravity-level (G) environment while seated and supine. During baseline data collection, the operator will identify the...

Eligibility Criteria

Inclusion

  • In coordination with the parabolic flight company, Novespace, healthy volunteers from the population that are 25-55 years old without a history cardiovascular disease will be recruited for this study. In order to participate, subjects must be able to follow instructions in English.
  • Participants must be age 18 years or older, hold a French or European Health Insurance Card, and provide medical certification of fitness for flight to NOVESPACE (i.e., NOVESPACE Parabolic Flight Medical Aptitude Certificate) completed by their medical doctor or an Authorized Medical Examiner.
  • Participants must meet medical criteria and provide certification of fitness for flight to NOVESPACE (i.e. NOVESPACE Parabolic Flight Medical Aptitude Certificate) completed by their medical doctor or an Authorized Medical Examiner.

Exclusion

  • NOVESPACE exclusion criteria includes:
  • Those with certain heart and lung conditions
  • dizziness
  • certain inner ear conditions
  • severe motor disability or impaired bone density
  • psychosis
  • mental disability prohibiting emergency evacuation
  • epilepsy
  • certain neurological diseases
  • fear of heights/flying
  • debilitating anxiety and panic attacks
  • claustrophobia, women who are pregnant
  • certain gastrointestinal conditions
  • those taking certain medications are ineligible to participate
  • An individual's overall medical fitness for flight is assessed and certified by a medical doctor or Authorized Medical Examiner.
  • Pregnant women are not eligible to participate in this study.

Key Trial Info

Start Date :

July 21 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 17 2024

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT06500338

Start Date

July 21 2022

End Date

April 17 2024

Last Update

September 19 2024

Active Locations (1)

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1

NASA

Houston, Texas, United States, 77058