Status:

RECRUITING

Non-invasive Tools for PSVD Diagnosis

Lead Sponsor:

Nanfang Hospital, Southern Medical University

Conditions:

Non-Cirrhotic Portal Hypertension

Porto-Sinusoidal Vascular Diseases

Eligibility:

All Genders

18-80 years

Brief Summary

Patients treated with platinum-based chemotherapy drugs have the probability of developing PSVD. The diagnosis of PSVD depends on liver biopsy. In addition, the level of portal vein pressure has guidi...

Detailed Description

PSVD is a supplement to non-cirrhotic portal hypertension and is defined as a class of diseases with characteristic pathological changes based on portal vein or hepatic sinuses abnormalities without c...

Eligibility Criteria

Inclusion

  • Received platinum chemotherapy for organ tumors;
  • Ages 18-80;
  • sign the informed consent voluntarily.

Exclusion

  • Liver pathology suggested cirrhosis;
  • Underwent liver transplantation;
  • Combined with hepatocellular carcinoma exceeding Milan criteria;
  • Complicated with severe heart, kidney, or lung failure;
  • Pregnant or lactating women;
  • Data is seriously missing;
  • Patients were judged not suitable for participation in this study by the researchers.

Key Trial Info

Start Date :

February 28 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2029

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT06500403

Start Date

February 28 2024

End Date

December 31 2029

Last Update

July 15 2024

Active Locations (1)

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1

Nanfang hospital, Southern Medical Uiversity

Guangzhou, Guangdong, China, 510080