Status:

RECRUITING

Effects of Vagus Nerve Pulmonary Branch Block on Postoperative Cough After VATS Lung Resection

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions:

Postoperative Cough

Thoracoscopy

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Postoperative cough after pulmonary resection is a common issue seen after thoracic surgeries, hindering patients' recovery and affecting their postoperative quality of life. While vagus nerve pulmona...

Eligibility Criteria

Inclusion

  • Age between 18 and 70 years old.
  • BMI between 18 and 30 kilograms per square meter (kg/m²).
  • ASA Physical Status Classification of I, II, or III.
  • Preoperative pulmonary imaging demonstrating peripheral lesions, with clinical staging T≤2, N≤1, M0.
  • Undergone thoracoscopic lung resection surgery.
  • Patients managed by the same lead surgeon's team.
  • Obtained informed consent, with patients agreeing and signing the informed consent document.

Exclusion

  • Patients with a history of chemotherapy or previous pulmonary surgery.
  • Presence of chronic cough due to respiratory infectious diseases, pharyngitis, rhinitis, COPD, asthma, post-nasal drip syndrome, etc.
  • Individuals exhibiting ECG abnormalities such as atrial fibrillation, bundle branch block, frequent ventricular premature beats, pre-excitation syndrome, etc.
  • Currently using ACE inhibitor medications.
  • Presence of preoperative hoarseness.

Key Trial Info

Start Date :

July 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

104 Patients enrolled

Trial Details

Trial ID

NCT06500949

Start Date

July 15 2024

End Date

July 1 2025

Last Update

July 29 2024

Active Locations (1)

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Second affiliated Hospital School of Medicine,Zhejiang University

Hangzhou, Zhejiang, China