Status:
RECRUITING
Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients
Lead Sponsor:
University of Colorado, Denver
Conditions:
Respiratory Failure
Acute Hypoxemic Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A multimodal educational intervention to target an oxygen saturation target range (SpO2 90-96%) will reduce ventilator length of stay and reduce occult hypoxemia by increased awareness and adherence t...
Detailed Description
This project will be a multi-hospital, cluster randomized study to implement a targeted oxygen saturation (SpO2) range of 90-96% in adult patients receiving mechanical ventilation (MV) using a multimo...
Eligibility Criteria
Inclusion
- Admission to ICU and requiring invasive mechanical ventilation
Exclusion
- Transferred patients from outside the UCHealth system\*:
- Patients with pre-existing disease that requires chronic use of positive pressure ventilation delivered through a tracheostomy\*:
- Pregnant women:
- Prisoners
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
3600 Patients enrolled
Trial Details
Trial ID
NCT06501118
Start Date
September 1 2024
End Date
July 31 2026
Last Update
December 24 2025
Active Locations (1)
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1
University of Colorado
Aurora, Colorado, United States, 80045