Status:

NOT_YET_RECRUITING

Effects of Individualized Theta-tACS on a Working Memory Training at SCD

Lead Sponsor:

University Hospital Tuebingen

Conditions:

Subjective Cognitive Decline

Eligibility:

All Genders

60+ years

Phase:

NA

Brief Summary

The aim of the study is to investigate the effects and mechanisms of action of an individualized transcranial alternating current stimulation in the theta-range (ITF-tACS) on a three day spatial worki...

Detailed Description

This study uses a randomized, double-blind, two-armed, sham-controlled between-subjects design. It is conducted at the University Hospital for Psychiatry and Psychotherapy Tübingen, Germany. Participa...

Eligibility Criteria

Inclusion

  • age \>/= 60 years
  • subjective cognitive decline with a duration \> 6 month and without a concrete cause
  • right-handedness (score \> 48 in the Edinburgh Handedness Inventory (EHI; Oldfield, 1971))
  • corrected or sufficient eyesight
  • sufficient knowledge in German
  • ability to consent

Exclusion

  • neuropsychiatric diagnose
  • score \> 13 in the DemTect (Kalbe et al., 2019)
  • score \> 4 in the Geriatric Depression Scale Short Form (GDS-SF; Sheikh \& Yesavage, 1986)
  • score \> 16 Geriatric Anxiety Scale German version(GAS-G; Gottschling et al., 2016)
  • substance abuse or dependence
  • epileptic seizure in medical history
  • metall in skalp-area
  • pacemaker
  • gravidity
  • psychiatric medication
  • benzodiazepines in a dosage \> 1 mg Lorazepam
  • participation in a tACS in history

Key Trial Info

Start Date :

July 19 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2025

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT06501755

Start Date

July 19 2024

End Date

July 31 2025

Last Update

July 15 2024

Active Locations (1)

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1

Universitätsklinik für Psychiatrie und Psychotherapie Tübingen, Neurophysiologie & Interventionelle Neuropsychiatrie, Tübingen, DE

Tübingen, Baden-Wurttemberg, Germany, 72076

Effects of Individualized Theta-tACS on a Working Memory Training at SCD | DecenTrialz