Status:
RECRUITING
Identification of New Gene Spliceosomes in Neuroblastoma
Lead Sponsor:
Affiliated Hospital of Nantong University
Conditions:
Neuroblastoma
Eligibility:
All Genders
1-14 years
Brief Summary
Neuroblastoma is an early childhood embryonic malignancy that originates from neural crest cells. Neuroblastoma shows high heterogeneity in biological, morphological, genetic, and clinical features. A...
Detailed Description
The clinical trial study aims to screen the genotype of children with neuroblastoma and conduct an in-depth analysis of sequencing data and tumor-specific transcripts using technologies--Deep Sequenci...
Eligibility Criteria
Inclusion
- Children with neuroblastoma range in age from 0 to 14, regardless of gender;
- Preoperative imaging examinations indicate patient with neuroblastoma;
- Before postoperative chemotherapy, the patient's physical strength is good. At the same time, the results of white blood cells, neutrophils, hemoglobin, platelets, and other test indicators are all within normal range, which is in line with the treatment conditions of the relevant chemotherapy and immunotherapy;
- Preoperative pathological examination of the patient reveals neuroblastoma;
- Patients have no other history of malignant tumors;
- Patients voluntarily participate and sign informed consent and can comply with the study visit plan and other protocol requirements.
Exclusion
- Patients who are found to have distant metastasis or ascites on preoperative examination are excluded;
- Patients with severe liver and kidney dysfunction, as well as those with autoimmune diseases are excluded;
- Patients with severe cardiovascular disease who can not tolerate general anesthesia are excluded;
- Patients who have other malignancies or blood disorders are excluded.
Key Trial Info
Start Date :
April 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06502210
Start Date
April 1 2024
End Date
August 31 2024
Last Update
July 16 2024
Active Locations (1)
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1
Affiliated Hospital of Nantong University
Nantong, Jiangsu, China