Status:

NOT_YET_RECRUITING

Modulatory Effect of Prodigiosin or Pioglitazone on TIME and the Crosstalk to Immune-Checkpoint Protein(s)

Lead Sponsor:

Ain Shams University

Conditions:

Lung Cancer

NSCLC

Eligibility:

All Genders

Brief Summary

Lung cancer is one of the most common and serious types of cancer. Lung tumor cells exploit immune checkpoint proteins (ICPs) to maintain immune tolerance and thus promote tumor progression and invasi...

Detailed Description

1\. Introduction 1.1. Background Components of the tumor microenvironment (TME) presented by immune cells, tumor cells, and their derived factors are known as Tumor immune microenvironment (TIME). Tum...

Eligibility Criteria

Inclusion

  • Adults over 50 years old with NSCLC.

Exclusion

  • Lung cancer patients with any cancer other than NSCLC
  • Lung cancer patients with incomplete data or incomplete histopathology diagnosis report.

Key Trial Info

Start Date :

June 1 2026

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2028

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06502249

Start Date

June 1 2026

End Date

September 1 2028

Last Update

July 16 2024

Active Locations (1)

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Faculty of Pharmacy, Ain Shams University, Advanced Biochemistry Research Lab

Cairo, Egypt, 11566