Status:
RECRUITING
Role of Interleukin-13 Pathways on Pain and Itch Sensitivity
Lead Sponsor:
Aalborg University
Conditions:
Itch
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Atopic dermatitis (AD) is as chronic, inflammatory skin disorder affecting 20% of the world's population. Intense itch and skin pain are the main symptoms. Research has shown that the proteins interle...
Detailed Description
Atopic dermatitis (AD) is as chronic, inflammatory skin disorder affecting 20% of the world's population. Intense itch and skin pain are the main symptoms. Research has shown that the interleukin-13 i...
Eligibility Criteria
Inclusion
- Healthy men and women
- 18-60 years
Exclusion
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids, or other drugs
- Previous or current history of neurological, dermatological (e.g., AD, psoriasis, etc.), immunological, musculoskeletal, cardiac disorder, or psychiatric diagnoses that may affect the results (e.g., neuropathy, muscular pain in the upper extremities, anxiety, depression, schizophrenia, etc.)
- Moles, wounds, scars, or tattoos in the area to be treated or tested
- Current use of medications that may affect the trial such as antihistamines and pain killers (use of antihistamines should be discontinued 72 hours before the experiment and all topical agents and emollients should be discontinued 24 hours before the experiment).
- Use of systemic and topical corticosteroids
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Acute or chronic pain
- Participation in other trials within one week of study entry (four weeks in the case of pharmaceutical trials)
- Lack of ability to cooperate
Key Trial Info
Start Date :
January 6 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06503510
Start Date
January 6 2025
End Date
December 31 2026
Last Update
June 4 2025
Active Locations (3)
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1
Aalborg University
Gistrup, Aalborg, Denmark, 9260
2
CNAP
Gistrup, Aalborg, Denmark, 9260
3
Aalborg University
Aalborg, Denmark, Denmark, 9260