Status:
RECRUITING
Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Lead Sponsor:
Centre for Infectious Disease Research in Zambia
Collaborating Sponsors:
University of Illinois at Chicago
University of Alabama at Birmingham
Conditions:
HIV Infections
Sexually Transmitted Diseases
Eligibility:
FEMALE
15-70 years
Phase:
NA
Brief Summary
The proposed hybrid effectiveness-implementation study will systematically adapt the Informed, Motivated, Aware, Responsible Adolescent Girls and Adults (IMARA) curriculum that was previously adapted ...
Detailed Description
The overall purpose of this study is to adapt the IMARA-SA curriculum for use in the Zambian context and test its impact on AGYW sexual behavior, as well as HIV and STI testing uptake and incidence, a...
Eligibility Criteria
Inclusion
- Adolescent girls and young women (AGYW)
- 15-19 years-old females (sex assigned at birth)
- Unmarried
- Residing outside the five study catchment areas
- Speak Nyanja, Bemba, or English or a combination (the primary regional languages)
- Willing and able to provide consent (\> 18 years old) and/or assent (\< 18 years old)
- Not known to be living with HIV (i.e., no positive test and not on ART)
- Mother Figures (MF)
- selected to participate by the AGYW
- if not the guardian/mother, agreed upon by the guardian/mother
- \> 24 years-old
- living with or in daily contact with the AGYW
- speak Nyanja, Bemba, or English or a combination
- Willing and able to provide consent
- Peer leaders (ZAIMARA \& Health Promotion)
- live in the community where they will be working
- have prior experience working with young people
- have a minimum grade 12 education
- be proficient in reading and writing English and/or Nyanja or Bemba
- are 22-29 years old for AGYW sessions
- are \>30 years-old for MF sessions
Exclusion
- AGYW
- AGYW who are enrolled in other SRH interventions at the time of recruitment (to prevent confounding) or are known to be living with HIV (the needs of AGYW living with HIV are unique and not well-addressed in IMARA-SA, e.g., learning to disclose) will be excluded. Importantly, AGYW who test positive for HIV at the study's baseline assessment will be able to complete the workshops and referred for treatment to avoid stigma.
Key Trial Info
Start Date :
April 7 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2028
Estimated Enrollment :
1200 Patients enrolled
Trial Details
Trial ID
NCT06503666
Start Date
April 7 2025
End Date
May 1 2028
Last Update
August 24 2025
Active Locations (1)
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1
Chainda, Matero, Chelston, Chongwe and Kalingalinga
Lusaka, Lusaka Province, Zambia, 10101