Status:

RECRUITING

Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Collaborating Sponsors:

Instituto de Salud Carlos III

Conditions:

Migraine Disorders

Eligibility:

All Genders

18-45 years

Brief Summary

The goal of this observational study is to identify differential traits in spontaneous migraine attacks that can help us predict the response to treatment with sumatriptan. Participants will be asked...

Detailed Description

There is still an unmet need in acute migraine treatment, some patients don't respond properly to acute medication. There are some interindividual differences in clinical characteristics of migraine ...

Eligibility Criteria

Inclusion

  • Migraine with or without aura diagnosis according to ICHD-3 criteria
  • \<8 migraine days per month
  • Be able to read, write and understand instructions.
  • Have internet access and mail address
  • Signing of the informed consent

Exclusion

  • Active preventive treatment for migraine
  • Active medication with an effect over the central nervous system
  • Serious physical or psychiatric condition
  • Cardiovascular or hepatic disease
  • Pregnant or breastfeeding women
  • Any triptan contraindication
  • Severe migraine attacks without previous response to triptans or NSAIDs

Key Trial Info

Start Date :

January 25 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

108 Patients enrolled

Trial Details

Trial ID

NCT06503848

Start Date

January 25 2024

End Date

December 1 2024

Last Update

October 28 2024

Active Locations (1)

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Hospital Universitari Vall d'Hebron

Barcelona, Spain

Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I | DecenTrialz