Status:

ENROLLING_BY_INVITATION

Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABA

Lead Sponsor:

Xiangya Hospital of Central South University

Conditions:

Chronic Cough

Eligibility:

All Genders

18+ years

Brief Summary

This study collected 600 patients, evaluated whether patients had airway hyperreactivity, airway inflammation, specific types and allergic reactions, comprehensively analyzed and classified the causes...

Detailed Description

The subjects of this study were patients with chronic cough who were admitted to the Department of Respiratory and Critical Care Medicine, Xiangya Hospital, Central South University from September 1, ...

Eligibility Criteria

Inclusion

  • Age ≥18 years old;
  • A clear history of COVID-19 infection with a positive nucleic acid or antigen test before chronic cough;
  • Persistent cough for more than 8 weeks after the acute phase of COVID-19 infection has disappeared;
  • Chest X-ray and/or chest CT without significant evidence of lung disease;
  • No history of chronic cough (\>8 weeks) prior to COVID-19 infection.

Exclusion

  • The patient refused pulmonary function and blood tests;
  • The patient has previously been diagnosed with respiratory diseases with cough as one of the main symptoms, including cough variant asthma, allergic bronchitis, eosinophilic bronchitis, gastroesophageal reflux disease, chronic obstructive pulmonary disease, chronic bronchitis, bronchiectasis, interstitial lung disease, pulmonary/tracheobronchial tuberculosis, etc.;
  • Patients who are pregnant or breastfeeding;
  • The patient's medical records are incomplete;
  • Patients lost to follow-up.

Key Trial Info

Start Date :

September 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT06503939

Start Date

September 1 2023

End Date

December 31 2024

Last Update

July 16 2024

Active Locations (1)

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Xiangya Hospital Central South University

Changsha, Hunan, China, 410008

Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABA | DecenTrialz