Status:

RECRUITING

Clocks in Sync - Circadian Rhythm and Bipolar Mania

Lead Sponsor:

Ottawa Hospital Research Institute

Conditions:

Bipolar Disorder

Mania

Eligibility:

All Genders

16+ years

Phase:

NA

Brief Summary

The sleep-wake cycle is severely disrupted during an episode of mania. Often mania is treated with medications that can come with significant side effects. Years of patient and family engagement with ...

Detailed Description

This pilot study will assess feasibility and preliminary data for a novel circadian intervention in a clinical population that has been understudied, patients dealing with manic episodes of bipolar di...

Eligibility Criteria

Inclusion

  • Be over age 16
  • Have DSM-5-defined manic symptoms that persist beyond the physiological effects of a substance and a YMRS≥20
  • Be willing to have investigators obtain information from the treatment team and electronic medical record
  • Participants must be able to read and understand English or French.
  • Be willing and able to provide informed consent.

Exclusion

  • Have a history of eating disorders.
  • Have a diagnosis of moderate to severe traumatic brain injury with residual or long-term effects, parenchymal brain surgery or stroke
  • Have a neurocognitive disorder
  • Take hypoglycemia-inducing medications
  • Be pregnant/lactating women
  • Have a diagnosis of sleep apnea
  • Have any other medical condition for which physician or investigator team expresses concern about safety or ability to participate in the study.

Key Trial Info

Start Date :

September 17 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06504342

Start Date

September 17 2024

End Date

October 1 2025

Last Update

January 17 2025

Active Locations (1)

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Ottawa Hospital Research Insitute

Ottawa, Ontario, Canada, K1Y 4E9