Status:
RECRUITING
SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom
Lead Sponsor:
NHS Greater Glasgow and Clyde
Conditions:
SCN1A
Dravet Syndrome
Eligibility:
All Genders
Brief Summary
The aims of this prospective natural history study are to define the seizure, neuro-developmental, and behavioural characteristics of SCN1A-related epilepsies/Dravet syndrome in children and adults lo...
Detailed Description
Our aim is to define the seizure, neurodevelopmental, and behavioural characteristics of SCN1A-related epilepsies/Dravet syndrome in children and adults longitudinally over a period of three years. In...
Eligibility Criteria
Inclusion
- Patients meeting the following inclusion criteria will be considered eligible for this study:
- Patient and/or legally authorised representative must be willing and able to give informed consent/assent for participation in the study.
- Patient and parent/caregiver are willing and able (in the Investigator's opinion) to comply with all study requirements (including ability and willingness to comply with virtual visits).
- Participant has a confirmed pathogenic (class 5) or likely pathogenic (class 4. SCN1A variant, as demonstrated by genetic testing.
- Exclusion criteria:
- Patient has any other significant disease or disorder which, in the opinion of the Investigator, may either put the patient at risk because of participation in the study, or may affect the patient's ability to participate in the study.
Exclusion
Key Trial Info
Start Date :
November 20 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06504511
Start Date
November 20 2023
End Date
June 1 2026
Last Update
July 16 2024
Active Locations (1)
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1
Royal Hospital for Children
Glasgow, United Kingdom, G51 4TF