Status:
RECRUITING
Biomarker Discovery in Lung Cancer - Malaysia
Lead Sponsor:
University of Malaya
Collaborating Sponsors:
MiRXES Pte Ltd
Conditions:
Lung Cancer
Eligibility:
All Genders
30+ years
Brief Summary
This study aims to 1. Identify biomarkers and signatures to differentiate between high-risk and lung cancer patients. 2. Discover blood-based biomarkers that can be used as an adjunct test to imaging...
Detailed Description
With existing evidence showing the utility of using liquid biopsy for early cancer detection, the investigators hypothesized that cell-free DNA and/or RNA expression changes during disease progression...
Eligibility Criteria
Inclusion
- Male or female subjects aged 30 and above.
- No previous history of any cancers.
- Able to provide X-ray and/or LDCT results.
- Have either COPD or pulmonary nodules measuring less than 11mm, or deemed not for biopsy by attending physician
- Willing to go back for a follow-up X-ray or LDCT scan in the next clinical follow up as per standard of care.
- Willing to provide up to 30mL of blood in month-0 (first visit) and up to 21mL in the next standard of care follow up visit (second visit).
Exclusion
- Subject has received chemotherapy or radiotherapy for cancer treatment, and any other cancer-related treatment.
- Subject is pregnant or lactating (self-declaration).
- Subject is unwilling or unable to provide signed informed consent
Key Trial Info
Start Date :
January 16 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06504927
Start Date
January 16 2024
End Date
December 31 2026
Last Update
July 18 2024
Active Locations (1)
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1
University of Malaya Medical Centre
Kuala Lumpur, Malaysia, 59100