Status:
NOT_YET_RECRUITING
Comparison of Topical Use of Platelet-rich Plasma Versus Hyaluronic Acid During Endoscopic Fat Graft Myringoplasty: a Randomized Clinical Study
Lead Sponsor:
Assiut University
Conditions:
Chronic Suppurative Otitis Media
Eligibility:
All Genders
14-50 years
Phase:
NA
Brief Summary
This study aimed to compare the effect of adding HA versus PRP to endoscopic FGM in cases of small or medium-sized central TM perforation in the form of: 1. Evaluation of the graft uptake rate. 2. Ev...
Detailed Description
Tympanic membrane (TM) perforations result in recurrent middle ear infection and hearing loss. Both these hazards can be prevented by the reconstructive surgery of the tympanic membrane. Fat graft my...
Eligibility Criteria
Inclusion
- Patients with central small or median sized dry perforation
- Aged between 14 and 50 years
- In cases of CSOM the perforation must be dry with no otorrhea with healthy middle ear mucosa for at least three month without medications
- Conductive gap on audiometry not more than 40 dB.
Exclusion
- Discharging CSOM .
- Concurrent URTI .
- CSOM with dry marginal perforation
- Patients who didn't come for follow up.
- Age less than 14 or more than 50.
- Unsafe CSOM with cholesteatoma, apparent retraction pockets, granulations, or extensive myringosclerosis reaching the edges of the perforation. Patients
- Patients who are suspected of having Eustachian tube dysfunction.
- Suspected ossicular pathology in safe CSOM if the ABG \> 40dB.
- Patients with history of Previous ear surgery.
- Patients unfit for surgery or having chronic medical illness.
- Narrow external auditory canal.
- Patients who refused to enrolled in our study
- Patients with sensorineural hearing loss or only functioning ear.
Key Trial Info
Start Date :
August 30 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 10 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06505252
Start Date
August 30 2024
End Date
October 10 2026
Last Update
July 17 2024
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