Status:

COMPLETED

Pulmonary Diffusing Capacity During Incremental Exercise in COPD

Lead Sponsor:

Rigshospitalet, Denmark

Conditions:

COPD

Healthy

Eligibility:

All Genders

40-80 years

Phase:

NA

Brief Summary

Background: The combined measurement of pulmonary diffusing capacity for carbon monoxide (CO) and nitric oxide (NO) (DL,CO,NO) has recently been standardized and validated for clinical use. It involv...

Detailed Description

Introduction and background A pattern that applies to the majority of the more than 250 million people who suffer from chronic obstructive pulmonary disease (COPD) worldwide, is a downward spiral of e...

Eligibility Criteria

Inclusion

  • Inclusion criteria for COPD patients
  • Men and women
  • 40-80 years
  • Mild to severe COPD (GOLD stage I to IIII)
  • Inclusion criteria for healthy participants
  • Men and women
  • Age +/- 3 years of an included COPD patient
  • Exclusion criteria for COPD patients
  • Known ischaemic heart disease
  • Known heart failure
  • Cardiac arrythmias
  • Dementia or other severe neurological disease
  • Known vascular ischaemic disease
  • Symptoms of infection (bacterial/viral) within 2 weeks prior to the study
  • Pregnancy
  • Exclusion criteria for heathy controls
  • COPD
  • Known ischaemic heart disease
  • Known heart failure
  • Cardiac arrythmias
  • Dementia or other severe neurological disease
  • Known vascular ischaemic disease
  • Symptoms of infection (bacterial/viral) within 2 weeks prior to the study
  • Pregnancy

Exclusion

    Key Trial Info

    Start Date :

    July 15 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    February 1 2025

    Estimated Enrollment :

    24 Patients enrolled

    Trial Details

    Trial ID

    NCT06505902

    Start Date

    July 15 2024

    End Date

    February 1 2025

    Last Update

    April 24 2025

    Active Locations (1)

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    1

    Center for Aktiv Sundhed (CFAS), Rigshospitalet, Copenhagen, Denmark.

    Copenhagen, København Ø, Denmark, 2100