Status:

TERMINATED

Functional and Non-Functional CSF Shunt Flow Measured With a Second-Generation Wireless Thermal Device

Lead Sponsor:

Rhaeos, Inc.

Conditions:

Hydrocephalus

Eligibility:

All Genders

Brief Summary

This study compares the performance of two generations of non-invasive cerebrospinal fluid (CSF) shunt flow assessment devices. Measurements of known non-functional and functional implanted shunts wil...

Eligibility Criteria

Inclusion

  • At least one existing ventricular CSF shunt, functional or non-functional (including an adjustable valve set to "virtual off," ligated shunt, uncorrected distal catheter disconnection or fracture, distal catheter fragment left in place during shunt surgery, or indication that the shunt is otherwise non-functional), with a region of overlying intact skin appropriate in size for application of the study device
  • If more than one distal shunt catheter is present, at least one distal shunt catheter is at least 2 cm away from any other distal shunt catheter in the device measurement region
  • Signed informed consent by subject or a parent, legal guardian, health care agent, or surrogate decision maker (according to local statutes)
  • Signed medical records release by subject or a parent, legal guardian, health care agent, or surrogate decision maker (according to local statutes)
  • Verbal assent by minors 7 years of age and older who are able to understand the study and communicate their decision

Exclusion

  • Presence of an interfering open wound or edema in the FlowSense device measurement area
  • Patient-reported history of adverse skin reactions to adhesives
  • Previous participation in a Rhaeos clinical study in which FlowSense device measurement data were acquired
  • New or worsening symptoms of a possible shunt malfunction in the prior 7 days
  • Use of the study device would interfere with standard patient care, or emergency surgery that cannot be delayed, or participation in the study will interfere with, or be detrimental to, administration of optimal healthcare to the subject
  • Participation in any other investigational procedural, pharmaceutical, and/or device study that may influence the collection of valid data under this study

Key Trial Info

Start Date :

July 27 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 27 2024

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06506045

Start Date

July 27 2024

End Date

July 27 2024

Last Update

May 15 2025

Active Locations (8)

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Page 1 of 2 (8 locations)

1

CHOC Commerce Tower

Orange, California, United States, 92868

2

Cedars-Sinai Accelerator

West Hollywood, California, United States, 90048

3

Tampa Marriott Water Street

Tampa, Florida, United States, 33602

4

MATTER

Chicago, Illinois, United States, 60611