Status:

COMPLETED

Unilateral Biportal Endoscopy Lumbar Interbody Fusion (ULIF) Versus Posterior Lumbar Interbody Fusion (PLIF) in Management of Single Level Lumbar Degenerative Disease: A Retrospective Study

Lead Sponsor:

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Conditions:

Lumbar Degenerative Disease

Eligibility:

All Genders

Brief Summary

The study aimed to compare the clinical efficacy and safety of unilateral biportal endoscopic lumbar interbody fusion (ULIF) with posterior lumbar interbody fusion (PLIF) in the treatment of single-le...

Eligibility Criteria

Inclusion

  • Patients who have been diagnosed with lumbar disc herniation, lumbar spinal stenosis, or lumbar spondylolisthesis based on their medical history, physical signs, and imaging exams such as lumbar anteroposterior and lateral radiographs (including hyperextension and hyperflexion positions), lumbar CT, and lumbar MR. (2) The patient has clear indications for surgical treatment: ① Conservative treatment for more than three months has been ineffective or the symptoms have continued to worsen ② The patient's symptoms are severe and interfere with their daily work and life ③ The patient exhibits signs of cauda equina nerve compression (such as numbness in the perineal area, loss of bowel and bladder control, etc.).
  • (3) The patient is undergoing their initial single-segment ULIF or PLIF surgery at our hospital.

Exclusion

  • Patients with lumbar degenerative diseases involving two or more segments
  • Pathological changes caused by other diseases, such as spinal infections, spinal trauma, spinal tumors, neurological diseases, etc.
  • Patients with lumbar spondylolisthesis exceeding Meyerding Grade II or degenerative scoliosis with a Cobb angle greater than 20 degrees
  • History of previous lumbar surgery
  • History of previous tumor disease.

Key Trial Info

Start Date :

November 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2024

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT06506500

Start Date

November 1 2022

End Date

May 1 2024

Last Update

July 17 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Sun Yat-sen Memorial Hospital, Sun Yat-sen University,

Guangzhou, Guangdong, China, 512000