Status:

ENROLLING_BY_INVITATION

Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy.

Lead Sponsor:

Taiho Oncology, Inc.

Conditions:

Advanced/Metastatic Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

This is a nonrandomized, open-label, multicenter rollover study for patients who received futibatinib as monotherapy or as combination therapy in a Taiho-sponsored futibatinib study.

Detailed Description

TAS-120-404 is a nonrandomized, open-label, multicenter rollover study for patients who received futibatinib as monotherapy or as combination therapy in a Taiho-sponsored futibatinib study. Patients ...

Eligibility Criteria

Inclusion

  • Provide written informed consent.
  • Receiving futibatinib as monotherapy or as combination therapy in an antecedent futibatinib study and deriving clinical benefit with no undue risk as assessed by the investigator.
  • Women of childbearing potential (WOCBP) must have a negative pregnancy test (urine or serum) within 7 days prior to receiving treatment. Both males and females of reproductive potential must agree to use effective birth control during study treatment and for a specified time after the last dose of study treatment.
  • Ability to take medications orally (PO) (feeding tube is not permitted).

Exclusion

  • • Has met any discontinuation criteria within the antecedent futibatinib study.

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT06506955

Start Date

October 1 2024

End Date

December 31 2026

Last Update

July 1 2025

Active Locations (9)

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Page 1 of 3 (9 locations)

1

University of California, San Francisco (UCSF)

San Francisco, California, United States, 94143

2

Institut Paoli-Calmettes

Marseille, France, 13009

3

Institut De Cancerologie Strasbourg

Strasbourg, France, 67033

4

Severance Hospital

Seoul, South Korea, 3722