Status:

COMPLETED

The Impact of Probiotics on Well-being in Women

Lead Sponsor:

Cultech Ltd

Collaborating Sponsors:

Comac Medical

Conditions:

Female

Healthy Aging

Eligibility:

FEMALE

45-65 years

Phase:

NA

Brief Summary

An exploratory study to determine whether daily supplementation with a probiotic product impacts the overall well-being of women aged between 45 - 65

Detailed Description

It is generally accepted that there is a gradual decline in general well-being associated with aging. In previous studies with healthy adults receiving the Lab4P probiotic the outcomes indicated an ov...

Eligibility Criteria

Inclusion

  • Women aged 45 to 65
  • Willing to provide faecal samples, blood samples and vaginal swabs
  • BMI of less than 30 kg/m2
  • Willing to maintain normal diet and lifestyle during the study
  • Willing to refrain from taking other probiotic supplements during the study
  • Normal (or corrected-to-normal) vision without colour blindness in order to complete the cognitive task

Exclusion

  • No oral antibiotics within the last 3 months
  • No previous been involvement in a Cultech funded study
  • No regular consumption of probiotics within the last 1 month prior to the study
  • Premature menopause (onset before age of 40)
  • Given birth in the last 3 months, currently pregnant or planning pregnancy
  • Receiving hormone replacement therapy
  • Shift worker
  • Diagnosed with diabetes
  • Immunodeficient or undergoing immunosuppressive therapy
  • Diagnosed with arrhythmia, ventricular extrasystole or atrioventricular block
  • Diagnosed with a cardiovascular disease
  • Diagnosed with a severe systemic disease e.g. cancer, dementia, advanced organ failure.
  • Unexplained loss of weight in recent months

Key Trial Info

Start Date :

July 30 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 5 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06507111

Start Date

July 30 2024

End Date

February 5 2025

Last Update

March 21 2025

Active Locations (1)

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Comac Medical

Sofia, Bulgaria