Status:
RECRUITING
The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis
Lead Sponsor:
Aydin Adnan Menderes University
Conditions:
Gingivitis
Eligibility:
All Genders
11-14 years
Phase:
NA
Brief Summary
This study aims to determine the levels of NLRP3, caspase-1 and IL-1β concentrations in the gingival crevicular fluid of paediatric patients with gingivitis and their changes after periodontal treatme...
Detailed Description
After being informed about the study and potential risks, necessary periodontal measurements will be performed and gingival crevicular fluid will be collected from all patients who gave written inform...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Inclusion criteria for the group with gingivitis;
- Systemically healthy
- 11-14 years old
- Permanent dentition
- No need for endodontic and restorative treatment
- Gingivitis with gingivitis
- Have verbally and in writing agreed to participate in the study and are willing to attend follow-up appointments regularly participants will be included in the study.
- Inclusion criteria for the healthy group;
- Systemically healthy
- 11-14 years old
- Permanent dentition
- No need for endodontic and restorative treatment
- Periodontally healthy
- Have verbally and in writing agreed to participate in the study and are willing to attend follow-up appointments regularly participants will be included in the study.
- Exclusion Criteria
- In need of endodontic and restorative treatment
- Systemically unhealthy
- Patients who do not give verbal or written consent
Exclusion
Key Trial Info
Start Date :
February 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06507280
Start Date
February 1 2024
End Date
January 1 2025
Last Update
July 18 2024
Active Locations (1)
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1
Sultan Keles
Aydin, Turkey (Türkiye), 09100