Status:

NOT_YET_RECRUITING

Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.

Lead Sponsor:

General Hospital of Ningxia Medical University

Conditions:

Outcome

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

This study aims to explore the effects of different application modes (prophylactic and rescue strategy) of norepinephrine and norepinephrine on neonate umbilical artery pH undergoing cesarean section...

Detailed Description

Spinal anesthesia-induced hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of spinal anesthesia-induced hypotension is as high as 62.1-89.7% if proph...

Eligibility Criteria

Inclusion

  • 18-45 years
  • Primipara or multipara
  • Singleton pregnancy ≥37 weeks
  • American Society of Anesthesiologists physical status classification II
  • Scheduled for cesarean section under spinal anesthesia

Exclusion

  • Body height \< 150 cm
  • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
  • Eclampsia or chronic hypertension or baseline blood pressure ≥140 mmHg
  • Hemoglobin \< 7g/dl
  • Fetal distress, or known fetal developmental anomaly

Key Trial Info

Start Date :

March 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2027

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT06508359

Start Date

March 1 2025

End Date

February 28 2027

Last Update

July 18 2024

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Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension. | DecenTrialz