Status:
RECRUITING
Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest
Lead Sponsor:
Byron Drumheller
Conditions:
Cardiac Arrest
Eligibility:
All Genders
18+ years
Brief Summary
Patients successfully resuscitated from sudden cardiac arrest are often comatose, having suffered a period of low blood flow and oxygen delivery to the brain. They are also at risk of suffering furthe...
Detailed Description
Patients who achieve return of spontaneous circulation (ROSC) after sudden cardiac arrest and remain comatose are at high risk of secondary brain injury that may prevent or worsen the quality of neuro...
Eligibility Criteria
Inclusion
- • Adults (\>=18 years old) resuscitated from out-of-hospital or in-hospital cardiac arrest who remain comatose (motor Glasgow coma scale \<=4) for at least 30 minutes when examined off sedation/neuromuscular blockade.
Exclusion
- Cardiac arrest due to traumatic brain injury, intracranial bleeding, or ischemic stroke
- Cervical spine fracture
- Need for immediate prone positioning for severe hypoxemic respiratory failure
- Marked hemodynamic instability precluding priority of any neuromonitoring (multiple recurrent cardiac arrests, norepinephrine equivalents \> 1.5 mcg/kg/min)
- Moribund neurological status based upon initial clinical, radiographic and historical assessment (e.g. diffuse cerebral edema or herniation on head computed tomography)
- Pregnancy
- Prisoners
Key Trial Info
Start Date :
September 20 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06511999
Start Date
September 20 2025
End Date
December 31 2027
Last Update
January 8 2026
Active Locations (1)
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1
UPMC Presbyterian Hospital
Pittsburgh, Pennsylvania, United States, 15213