Status:

RECRUITING

Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders

Lead Sponsor:

University of Pennsylvania

Conditions:

Placenta Accreta Spectrum

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This study for the conservative management of placenta accreta spectrum disorders (PAS), which are a major cause of maternal morbidity and mortality. The most common management strategy for PAS in the...

Eligibility Criteria

Inclusion

  • Provision of signed and dated informed consent form.
  • Stated willingness to comply with all study procedures and availability for the duration of the study.
  • A person with a uterus, age 18 or older
  • Currently 16-36 weeks pregnant with an intrauterine gestation
  • History of cesarean delivery AND placenta previa OR anterior low-lying placenta AND suspected of having PAS on prenatal imaging (ultrasound/MRI)
  • Patients for whom the usual management would be cesarean-hysterectomy.
  • Patient desires uterine preservation
  • Agreement to adhere to Lifestyle Considerations (see section 5.3) throughout study duration.

Exclusion

  • • Have a low antenatal suspicion for PAS based on imaging.

Key Trial Info

Start Date :

April 21 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2030

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT06512181

Start Date

April 21 2025

End Date

December 31 2030

Last Update

April 30 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104