Status:
NOT_YET_RECRUITING
10 Vs.15 mcg Norepinephrine Bolus in Severe Maternal Hypotension During Cesarean Delivery
Lead Sponsor:
Cairo University
Conditions:
Hypotension
Spinal Anesthesia
Eligibility:
FEMALE
18-40 years
Phase:
NA
Brief Summary
Data regarding the optimum dose of norepinephrine for management of severe maternal hypotension is lacking. A previous report showed that the use of 10-mcg norepinephrine bolus was not superior to the...
Detailed Description
Upon arrival to the operating room, the patient will be in supine position with left uterine displacement using a wedge below the right buttock. Routine monitoring will be applied (electrocardiography...
Eligibility Criteria
Inclusion
- full-term singleton pregnant women
- American society of anesthesiologist II, scheduled for elective cesarean delivery,
Exclusion
- Patients with uncontrolled cardiac morbidities (patients with tight valvular lesion, impaired contractility with ejection fraction \< 50%, heart block, and arrhythmias),
- hypertensive disorders of pregnancy,
- peripartum bleeding,
- coagulation disorders (patients with INR \>1.4 and or platelet count \< 80000 /dL) or any contraindication to regional anesthesia,
- baseline systolic blood pressure (SBP) \< 100 mmHg
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
184 Patients enrolled
Trial Details
Trial ID
NCT06512415
Start Date
August 1 2024
End Date
December 1 2024
Last Update
July 22 2024
Active Locations (1)
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1
Cairo University
Cairo, Egypt