Status:

ACTIVE_NOT_RECRUITING

A Clinical Study to Assess the Efficacy of Cannabigerol in Patients with Active Rheumatoid Arthritis.

Lead Sponsor:

Raphael Pharma

Collaborating Sponsors:

Citruslabs

Conditions:

Rheumatoid Arthritis

Inflammatory Disease

Eligibility:

All Genders

25+ years

Phase:

NA

Brief Summary

This is a single-group exploratory longitudinal prospective study lasting 8 weeks. The study aims to measure the efficacy of purified cannabigerol (CBG) in patients with active rheumatoid arthritis us...

Eligibility Criteria

Inclusion

  • Male or female, over 25 years of age
  • Positive anti-CCP blood test
  • Active RA-related inflammation with at least 2 swollen joints
  • University graduate
  • Generally healthy with no uncontrolled chronic disease
  • Able to read, understand, and sign informed consent
  • Resides in the USA
  • Willing to comply with study requirements and avoid other cannabis products during the study period

Exclusion

  • Pre-existing chronic conditions preventing adherence
  • Severe allergic reactions requiring an Epi-pen
  • Use of opiates in the last 4 weeks or cannabis in the last 8 weeks
  • Pregnant or breastfeeding women
  • Recent invasive medical procedure or surgery
  • Active malignancy or ongoing oncology treatment
  • Use of cytochrome P450 or 3A4 inhibitors
  • History of substance abuse

Key Trial Info

Start Date :

June 3 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2024

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT06513507

Start Date

June 3 2024

End Date

December 31 2024

Last Update

November 21 2024

Active Locations (1)

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1

Citruslabs

Santa Monica, California, United States, 90404