Status:
RECRUITING
Exercise as Maintenance Therapy in Advanced Lung Cancer
Lead Sponsor:
Indiana University
Conditions:
Lung Cancer
Non Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to examine how a multimodality (having or using a variety of methods to do something) exercise intervention may improve survival, function, and quality of life in particip...
Detailed Description
This study is a randomized control trial at a single institution comparing advanced lung cancer patients undergoing supervised home-based exercise program versus usual care. The intervention is a supe...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Known diagnosis of locally advanced (stage III) or metastatic NSCLC
- Patient is currently receiving maintenance immunotherapy for at least 1 month and planned for at least 3 additional months of therapy
- Patients receiving maintenance therapy refers to patients with stable disease or partial response to therapy, including patients who have had a history of disease progression but are currently stable or responding to a different therapy
- Patients previously receiving chemotherapy are eligible as long as at least one month has elapsed since completing chemotherapy. Those currently receiving chemotherapy are not eligible.
- Patient is willing and able to participate in a supervised home-based exercise program as determined by the MOVE program
- a.Participants must have internet access and equipment to participate in virtual exercise
- ECOG performance status of 0-2
Exclusion
- Already meeting exercise guidelines and participating in at least 150 minutes of moderate or vigorous exercise per IPAQ
- Unable to participate in the supervised home-based exercise program as determined by the MOVE program
- Medical co-morbidities that preclude patient from participating in supervised exercise, including but not limited to:
- Advanced heart failure
- Advanced respiratory disease requiring home oxygen use
- Uncontrolled psychiatric disorders
- History of fragility fracture
Key Trial Info
Start Date :
October 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2029
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06513663
Start Date
October 15 2024
End Date
December 1 2029
Last Update
May 1 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Indiana University Health Methodist Hospital
Indianapolis, Indiana, United States, 46202
2
Indiana University Melvin & Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States, 46202
3
Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana, United States, 46202