Status:
ACTIVE_NOT_RECRUITING
Activity of Bioactive Natural Compounds as Potential Agonists of GLP1R
Lead Sponsor:
Universidad Católica San Antonio de Murcia
Conditions:
Obesity
Overweight
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if natural bioactive compound jubenine works to reduce appetite and to favour weight loss. It will also learn about the safety of natural bioactive compound...
Detailed Description
The general objective of the present project is to confirm the activity of non-peptide compounds from bioactive natural sources, concretely jubenine, which will be a GLP1R agonists for their potential...
Eligibility Criteria
Inclusion
- BMI over 24.9
- no clinically relevant abnormalities and no relevant systemic disease history
Exclusion
- the presence of any clinically relevant symptoms or severe disease within 4 weeks of the start of the study
- any history of hepatic dysfunction, any condition that might affect the pharmacokinetics properties of the study drug.
- diarrhoea (\>2 liquid stools per day) or constipation (3 days duration) 1 week prior to the start of the study
- history of hypersensitivity to GLP1R agonists
- evidence of hepatitis B or C, HIV positivity
- smoking (\>4 cigarettes/day)
- history of alcohol or substance abuse
- bulimia or laxative abuse
Key Trial Info
Start Date :
January 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06513715
Start Date
January 9 2024
End Date
July 1 2026
Last Update
July 22 2024
Active Locations (1)
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1
Faculty of Nursing. Catholic University of Murcia
Murcia, Spain, 30107